The Southern District of Florida can pull jurors from its nine counties: Broward, Dade, Highlands, Indian River, Martin, Monroe, Okeechobee, Palm Beach and St. Lucie.

Six of the counties supported Trump over his Democratic rivals in the 2016 and 2020 elections, though in St. Lucie, the Trump vote hovered at around 50%. Highlands, Indian River, Martin and Okeechobee counties are the strongest GOP strongholds, with over 60% of voters having supported Trump in the 2016 and 2020 elections.

Broward, Miami-Dade and Palm Beach counties voted for Hillary Clinton in 2016 and Joe Biden in 2020.

In Miami-Dade County, typically a stronghold for the party, Democrats lost significant ground in 2020. In 2016, 64% of voters went to Clinton, while in 2020, 53.4% of voters went to Biden.

The other counties had similar levels of support for each party's candidate in 2016 and 2020.

Asa Hutchinson, the former Arkansas governor who is running for the 2024 Republican presidential nomination, said Trump should end his bid for another term in the White House now that he has been indicted in the classified documents case.

"Donald Trump is entitled to the presumption of innocence," Hutchinson said in a statement. But "the ongoing criminal proceedings will be a major distraction. This reaffirms the need for Donald Trump to respect the office and end his campaign."

"Donald Trump’s actions—from his willful disregard for the Constitution to his disrespect for the rule of law—should not define our nation or the Republican Party," said Hutchinson, who has said the U.S. needs to go in a "different direction" following Trump's four years in the Oval Office.

Some congressional Republicans have reacted to Trump's indictment by trying to connect it with unproven allegations that Biden was involved in a bribery scheme as vice president.

Sen. Chuck Grassley, R-Iowa, tweeted that the indictment came the same day he said the FBI restricted access to redacted allegations about Biden.

Rep. Wesley Hunt, R-Texas, tweeted a similar message, saying Trump was indicted on the same day the FBI allowed members of the House Oversight Committee to view a document purportedly about Biden.

Asked about the document earlier Thursday, Biden said, "It's a bunch of malarkey."

Chris Christie, the former New Jersey governor and GOP presidential contender who has positioned himself as a vociferous Trump critic, will wait to comment until he can review the text of the indictment and address specifics, sources close to Christie said.

Christie, a former federal prosecutor, endorsed Trump early in the 2016 presidential cycle but has since gone on a blunt offensive against the Republican front-runner.

Some Trump defenders levied charges the U.S. has become a “banana republic” after news that the former president has been indicted federally, while others said it was a good day for the rule of law.

Rep. Troy Nehls, R-Texas, and Trump’s son, Donald Trump Jr., were among those criticizing the news, which Trump himself shared on his social media platform, Truth Social.

“We live in a Banana Republic,” Nehls tweeted.

Rep. Nancy Mace, R-S.C., predicted on Fox News that the indictment would lead to Trump’s nomination as the GOP presidential nominee in 2024. She repeated “banana republic” on the network.

House Speaker Kevin McCarthy, R-Calif., and Senate Minority Leader Mitch McConnell, R-Ky., did not immediately comment.

Rep. Adriano Espaillat, D-N.Y., tweeted "A friendly reminder… no one is above the law. Not even a former President.

Pence will appear on Fox News at 9 p.m. ET for an interview with host Sean Hannity, the new 2024 presidential candidate tweeted.

The tweet was sent before news of his former boss' second indictment broke.

Members of Congress were quick to react tonight to Trump's indictment, though leaders of both chambers have yet to weigh in.

Rep. Jim Jordan, R-Ohio, tweeted: "Sad day for America. God Bless President Trump."

Republicans on the House Judiciary Committee, led by Jordan tweeted: “WITCH HUNT."

Across the aisle, Rep. Adam Schiff, D-Calif., tweeted: "For four years, he acted like he was above the law. But he should be treated like any other lawbreaker. And today, he has been."

Rep. Rashida Tlaib, D-Mich., tweeted, "The former twice-impeached president is now twice-indicted."

Trump released a 4-minute video on Truth Social arguing that he's innocent of the indictment against him and that he has been targeted for seven years since he ran for president.

"They can’t stop, because it’s election interference at the highest level. There’s never been anything like what’s happened. I’m an innocent man. I’m an innocent person," he said.

He said that it is "warfare" and that the country is "going to hell."

"We can't let this continue to go on, because it's ripping our country to shreds. We have such big problems, and this shouldn't be one of them," he said. "It's a hoax. The whole thing is a hoax, just like Russia, Russia, Russia. Just like the fake dossier was a hoax."

Trump continued: "So, I just want to tell you, I'm an innocent man, I did nothing wrong. And we will fight this out just like we've been fighting for seven years. It would be wonderful if we could devote our full time to making America great again."