First Steve Smith, and now Hakeem Nicks: The wide receiver will miss at least three weeks with compartment syndrome in his right leg — removing yet another of Eli Manning’s targets at a crucial point in the season as the Giants look to stop a two-game losing streak. (Via the Post, compartment syndrome is “a swelling in the lower leg that compresses nerves and blood vessels.”) The Giants probable starters on Sunday? Mario Manningham and Derek Hagan, who’s been on the team for all of one week. The only other healthy receiver on the roster right now is rookie Duke Calhoun, though the Giants are bringing in Michael Clayton, currently playing for the Omaha Nighthawks of the UFL, for a workout. [NYP]